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Cell Signaling Technology U-18666A, Cholesterol Transport Inhibitor, 5 mg
SDP

Catalog No. 502050551
Encompass

U-18666A is a cell-permeable small molecule that functions as a potent inhibitor of intracellular cholesterol transport. By blocking low-density lipoprotein (LDL)-derived cholesterol trafficking, this compound prevents cholesterol esterification and suppresses LDL receptor activity. It is widely utilized in research to simulate intracellular cholesterol accumulation, providing a valuable tool for investigating the pathogenesis of neurological disorders, such as Alzheimer™ disease and Niemann-Pick disease type C, as well as atherosclerosis and viral infection mechanisms.

  • Inhibits LDL-derived cholesterol transport and esterification
  • Suppresses LDL receptor activities
  • Useful for studying intracellular cholesterol accumulation and neurodegenerative pathologies
  • Relevant for research on viral entry and replication
  • Supplied as a lyophilized powder

Catalog No. 50-205-0551 Supplier Cell Signaling Technology Supplier No. 68998S
May include imposed supplier surcharges.
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U-18666A is a cell-permeable small molecule that functions as a potent inhibitor of intracellular cholesterol transport. By blocking low-density lipoprotein (LDL)-derived cholesterol trafficking, this compound prevents cholesterol esterification and suppresses LDL receptor activity. It is widely utilized in research to simulate intracellular cholesterol accumulation, providing a valuable tool for investigating the pathogenesis of neurological disorders, such as Alzheimer™ disease and Niemann-Pick disease type C, as well as atherosclerosis and viral infection mechanisms.

  • Inhibits LDL-derived cholesterol transport and esterification
  • Suppresses LDL receptor activities
  • Useful for studying intracellular cholesterol accumulation and neurodegenerative pathologies
  • Relevant for research on viral entry and replication
  • Supplied as a lyophilized powder

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