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Enzo Life Sciences U-18666A (50 mg). CAS: 3039-71-2
Supplier: Enzo Life Sciences BMLS2000050
A useful tool for inhibition of cholesterol transport from late endosomes/lysosomes to the endoplasmic reticulum. Inhibits cholesterol transport in a variety of cell types such as macrophages and sympathetic neurons. May be used to induce a Neimann-Pick disease type C (NPC)or NPC-like phenotype in a variety of cell types. Inhibits cholesterol biosynthesis at the level of oxido-squalene cyclase (OSC). Induction of cataracts is a common toxic feature of OSC inhibitors such as U18666A. Alternative name: 3beta-(2-Diethylaminoethoxy)-Androstenone . HCl. Purity: ≥99% (TLC). Long Term Storage: Ambient.
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