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Apexbio Technology LLC U-73122 5mg. MFCD22683852.

Supplier: Apexbio Technology LLC B34225

U-73122 is a potent phospholipase C (PLC) inhibitor with IC50 value of ~6 μM. PLC is a class of membrane-associated enzymes that catalyzes the hydrolysis of a membrane phospholipid, phosphatidylinositol 4,5-bisphosphate (PIP2), to produce two intracellular messengers, diacylglycerol and inositol-triphosphate, which, in turn, mediate the activation of protein kinase C (PKC) and intracellular Ca2+ release, respectively. It plays an important role in various signal transduction pathways. Other sizes are available. Please inqury us for quote.
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