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Medchemexpress LLC U-99194 maleate | 234757-41-6 | 99.2% | 10 MG
Supplier: Medchemexpress LLC HY12701A10MG
U-99194 maleate is a selective, potent dopamine D3 receptor antagonist with a Ki of 160 nM. It inhibits the activation of the D3 receptor mediated by endogenously released dopamine or exogenous D3 agonists. This compound can be used for the study of dopamine D3 receptor-mediated motor disorders, particularly kinetic tremors.
- Selective, potent dopamine D3 receptor antagonist
- Inhibits activation of D3 receptor
- Abrogates IPSC-suppressive effect of D3 agonist PD 128907 in rat hippocampal slices
- Significantly suppresses nicotine-induced tremor in mice
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