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Medchemexpress LLC U-99194 maleate (U-99194A) | 234757-41-6 | 99.2% | 50 MG
SDP

Supplier:  Medchemexpress LLC HY12701A50MG

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U-99194 (PNU-99194) maleate is a selective and potent dopamine D3 receptor antagonist. It inhibits the activation of D3 receptors mediated by endogenously released dopamine or exogenous D3 agonists. This compound can be used for the study of dopamine D3 receptor-mediated motor disorders, particularly kinetic tremors.

  • Selective, potent dopamine D3 receptor antagonist (Ki = 160 nM).
  • Inhibits D3 receptor activation.
  • Abrogates IPSC-suppressive effect of D3 agonist PD 128907 in rat hippocampal slices.
  • Significantly suppresses nicotine-induced tremor in mice.
  • Useful for studying dopamine D3 receptor-mediated motor disorders, especially kinetic tremors.

Catalog No. 50-003-41566


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