Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Eurofins Discoverx InCELL Hunter U2OS Bcl2-Bax Protein Binding Cell Line, 2 vials. (96-0010C3)
Supplier: Eurofins Discoverx 960010C3
The InCELL Hunter U2OS Bcl2-Bax Protein Binding Cell Line provides an easy-to-use cell based assay to study small molecule drug candidates that disrupt protein binding. This kit assesses compound-based disruption of Bcl2-Bax binding via detection of Bax levels. This product uses EFC technology. The cell line included overexpresses Bcl2 target in an untagged form and Bax binding partner fused to ProLabel. When a compound engages the Bcl2 target protein, partner binding is disrupted and the destabilized Bax is degraded, leading to a loss of EFC signal upon addition of EA containing detection reagent. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?