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Eurofins Discoverx PathHunter U2OS BMPR1A/BMPR2 Dimerization Cell Line, 2 vials. (93-1006C3)
Supplier: Eurofins Discoverx 931006C3
The PathHunter BMPR1A/BMPR2 Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. BMP-4) induced dimerization of BMPR1A/BMPR2 receptors. This product uses EFC technology. The cell line included overexpresses BMPR2 target protein fused to PK alongside BMPR1A target protein fused to EA. Upon ligand-induced dimerization of BMPR1A/BMPR2, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
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