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Eurofins Discoverx PathHunter U2OS β-Catenin Nuclear Translocation Cell Line, 2 vials. (93-0743C3)
Supplier: Eurofins Discoverx 930743C3
The PathHunter U2OS β-Catenin Nuclear Translocation Cell Line is a stable, engineered cell line for use in studying drug candidates affecting the Wnt-FzGSK3β pathway. This cell line enables assessment of ligand (e.g. wnt 3a) based pathway activation via detection of resulting β-Catenin nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged β-Catenin and nuclear localized EA. Upon pathway activation, induced nuclear translocation of β-Catenin leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/pathways.
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