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Eurofins Discoverx PathHunter U2OS FGFR3(G380R)/FGFR3(G380R) Dimerization Cell Line, 2 vials. (93-1091C3)
Supplier: Eurofins Discoverx 931091C3
The PathHunter FGFR3(G380R)/FGFR3(G380R) Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. FGF-18) induced dimerization of FGFR3/FGFR3 receptors. This product uses EFC technology. The cell line included overexpresses FGFR3G380R target protein fused to PK alongside FGFR3G380R target protein fused to EA. Upon ligand-induced dimerization of FGFR3(G380R)/FGFR3(G380R), detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the G380R version of FGFR3. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
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