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Eurofins Discoverx PathHunter U2OS mHTR2C β-Arrestin Cell Line, 2 vials. (93-0790C3)
Supplier: Eurofins Discoverx 930790C3
The PathHunter mHTR2C cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin) based activation of mHTR2C GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mHTR2C and EA-tagged β-Arrestin-2. Activation of mHTR2C stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
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