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Eurofins Discoverx PathHunter U2OS p53 Nuclear Translocation Cell Line, 2 vials. (93-0757C3)
Supplier: Eurofins Discoverx 930757C3
The PathHunter U2OS p53 Nuclear Translocation Cell Line is a stable, engineered cell line for use in studying drug candidates affecting the p53 DNA damage pathway. This cell line enables assessment of ligand (e.g. camptothecin) based pathway activation via detection of resulting p53 nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged p53 and nuclear localized EA. Upon pathway activation, induced nuclear translocation of p53 leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/pathways.
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