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Eurofins Discoverx PathHunter U2OS PRβ Nuclear Translocation Cell Line, 2 vials. (93-0484C3)
Supplier: Eurofins Discoverx 930484C3
The PathHunter PRβ Nuclear Translocation cell line is a stable, engineered cell line for use in studying drug candidates affecting NHR activation and nuclear translocation. This cell line enables assessment of ligand (e.g. testosterone, norgestrel) based NHR activation via detection of resulting PRβ (progesterone receptor beta) nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged PRβ NHR and nuclear localized EA. Upon activation of PRβ, induced nuclear translocation leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/nhr.
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