Apexbio Technology LLC ubiquitin specific protease 3 fragment 5mg

Supplier:  Apexbio Technology LLC A10975

Ubiquitin specific protease 3 fragment is a human chromatin-associated deubiquitinating enzyme (DUB) targeting ubiquitinated histones H2A and H2B It is designed to remove ubiquitin from these histones thereby modulating chromatin structure and regulating DNA replication and damage response pathways Ubiquitin specific protease 3 fragment exerts its biological activity primarily through the zinc-finger ubiquitin-binding domain (ZnF-UBP) mediating interaction with ubiquitinated histones and facilitating their deubiquitination In RNA interference-based targeting studies USP3 fragment regulates DNA replication by preventing accumulation of DNA breaks and replication stress in S phase Based on these pharmacological properties ubiquitin specific protease 3 fragment holds research potential in studying chromatin remodeling histone ubiquitination dynamics and DNA repair pathways

Catalog No. 50-000-93121