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Cayman Chemical UbIquItInlIkSpecIfIc Prote
Supplier: Cayman Chemical 41844500 UG
An aglycone with diverse biological activities inhibits the proliferation and migration of A549 H1299 H1975 and SK-MES-1 lung cancer cells from 10-50 UM induces AMPK activation and autophagy as well as apoptosis and cell cycle arrest at the G1 phase in A549 cells at 50 UM reduces tumor weight and volume in an A549 mouse xenograft model at 10 mg/kg reduces colonic inflammatory cell infiltration and colonic shortening in a mouse model of DSS-induced ulcerative colitis at 5 mg/kg improves LPS-induced memory impairments and decreases hippocampal and frontal cortex levels of TNF-a IL-1B and IL-6 in LPS-challenged mice
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