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Abcam UBP310, GluK1 and GluK3 selective antagonist, 50MG
Supplier: Abcam AB12016850MG
MW 353.35 Da, Purity >98%. GluK1 (formerly GluR5) and GluK3 (formerly GluR7) receptor selective antagonist (Kb =10 nM and IC₅₀ = 23 nM, respectively). IC₅₀ values are >100 μM at recombinant human GLUA2 (formerly GluR2), GluK2 (formerly GluR6,) GluK2/GluK5 (formerly GluR6/KA2) and GluK2/GluK3 (formerly GluR6/GluR7). Selective over native AMPA receptors (Kd = 83 μM) and exhibits no activity at NMDA and Group I mGlu receptors at concentrations of up to 10 μM.
The product is subject to the following: Abcam Restricted Use Statement
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