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Medchemexpress LLC UC-112 | 383392-66-3 | 98.9% | 50 MG
Supplier: Medchemexpress LLC HY1284250MG
UC-112 is a survivin and XIAP modulator that demonstrates anticancer activity. It works by selectively downregulating and degrading survivin through the ubiquitin-mediated proteasomal degradation pathway. It also reduces XIAP levels in in vivo tumor models, activates caspase-3/7 and caspase-9, and induces apoptosis in cancer cells. This product is for research use only and not for patient use.
- Selectively downregulates and degrades survivin
- Reduces XIAP levels in in vivo tumor models
- Activates caspase-3/7 and caspase-9, inducing cancer cell apoptosis
- Inhibits proliferation of A375, M14, PC-3, and DU145 cancer cells
- Inhibits human melanoma tumor growth in nude mice
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