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Medchemexpress LLC UC2288 | 1394011-91-6 | 99.8% | 481.82 | 250 MG
Supplier: Medchemexpress LLC 250MGHY112780
UC2288 is a potent and orally active p21 attenuator with relatively selective activity for p21. It is synthesized based on Sorafenib and potently inhibits cancer cell growth by inducing apoptosis. UC2288 shows no inhibition of VEGFR2 and Raf kinases even at 10 μM.
- Potent and orally active p21 attenuator
- Induces apoptosis to inhibit cancer cell growth
- Relatively selective activity for p21
- No inhibition of VEGFR2 and Raf kinases at 10 μM
- Decreases p21 protein level and mRNA expression
- Suppresses tumor growth in vivo
- Ameliorates MPTP-induced Parkinson's disease progression
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