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AdipoGen UK 5099

Supplier: AdipoGen AGCR13691M010
Chemical. CAS 56396-35-1. Formula C18H12N2O2. MW 288.3. . Potent and specific inhibitor of the mitochondrial pyruvate carrier MPC, blocking pyruvate from entering the mitochondria, consequently promoting lactate production. Inhibitor of tricarboxylic acid TCA cycle. Plasma membrane monocarboxylate transporters MCTs inhibitor, but with Ki values some two or three orders of magnitude higher than those for the inhibition of the MPC. Inhibits mitochondrial lactate and pyruvate transport. Decreases glycolysis. Useful agent for immunometabolism research.
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