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Apexbio Technology LLC Ulipristal 159811-51-5 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B21345.1
Ulipristal is a selective progesterone receptor modulator (SPRM) exhibiting tissue-specific agonist and antagonist activities on progesterone-sensitive targets It functions through competitively binding to the progesterone receptor thereby modulating downstream cellular and physiological responses Ulipristal has been explored in biomedical research primarily for emergency contraception administered within 120 hours following unprotected intercourse Additionally ulipristal demonstrates potential utility in managing benign gynecological disorders such as uterine fibroids (leiomyomas) by mediating apoptosis in myomatous cells and controlling cellular proliferation In vitro studies indicate that ulipristal acetate inhibits progesterone-stimulated acrosome reactions and hyperactivation of human spermatozoa highlighting its potential receptor-mediated modulation of sperm functions
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