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Cayman Chemical UmbelIprenIn 10mg
Supplier: Cayman Chemical 2789410 MG
A prenylated coumarin with diverse biological activities; inhibits 5-LO in a cell-free assay (IC50 = 72.5 nM); active against L. major promastigotes (IC50 = 13.3 µM); induces cell cycle arrest at the G1 phase in, as well as inhibits the growth of (IC50 = 12.5 µM), M4Beu metastatic pigmented melanoma cells; reduces tumor volume in a mouse Lewis lung carcinoma model; reduces tumor growth and the number of metastases in a 4T1 mouse allograft model; reduces carrageenan-induced paw edema in mice at 0.01 mmol/kg
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