ATCC UMCHOR1 CHORDOMA HUMAN HOMO SA

Supplier:  ATCC CRL3270

UM-Chor1 is a mesangial cell line that was isolated in 2012 from the clivus of a 64-day-old, White male patient with chordoma. UM-Chor1 is the first known human clival chordoma established. It exhibits chordoma-like characteristics and has molecular, genetic, and morphological features typical of chordoma. This cell line was established from a suprasellar lesion with solid, cystic, and hemorrhagic components. It extended along the clivus, and into the ethmoid sinuses. The resultant cultures were purified by flow cytometry and the population of cells staining positive for neural cell adhesion molecule (NCAM) were expanded as the UM-Chor1 chordoma cell line. Chordoma is a rare slow growing tumor type, and UM-Chor1 is a relatively slow growing cell line. The cells express the transcription factor T (Brachyury) that is the most specific marker for chordoma. This cell line was accessioned with the support of the Chordoma Foundation, a nonprofit organization working to improve the lives of c

Catalog No. 50-238-2021