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Medchemexpress LLC Umeclidinium bromide | 869113-09-7 | 508.49 | 250 MG
Supplier: Medchemexpress LLC 250MGHYW004415
Umeclidinium bromide is a novel mAChR antagonist with high affinity for cloned human M1-M5 mAChRs. It exhibits slow functional reversibility at cloned human M3 mAChRs and at endogenous mAChR in isolated human bronchus. It also inhibits the human ether-a-go-go-related gene channel tail current in human embryonic kidney 293 cells.
- Target: mAChR
- Pathway: GPCR/G protein, neuronal signaling
- Inhibits human ether-a-go-go-related gene channel tail current
- Demonstrates slow functional reversibility at M3 mAChRs
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