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Medchemexpress LLC Umeclidinium (bromide) | 869113-09-7 | 508.49 | 500 MG
SDP

Supplier:  Medchemexpress LLC HYW004415500MG

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Umeclidinium bromide is a novel mAChR antagonist with high affinity (Ki) for cloned human M1-M5 mAChRs, ranging from 0.05 to 0.16 nM. It is intended for research use only and not for patient use.

  • Inhibits the human ether-a-go-go-related gene channel tail current in human embryonic kidney 293 cells (IC50=9.4 μM).
  • Potent agent demonstrating slow functional reversibility at cloned human M3 mAChRs and at endogenous mAChR in isolated human bronchus.
  • Utilized in ligand binding assays with [3H]-N-methyl scopolamine for mAChR characterization.
  • Applicable for in vitro studies and in vivo experiments in mice.

Catalog No. 50-004-46271


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