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Apexbio Technology LLC UNC 0642(Synonyms: UNC0642, UNC-0642, G9a/GLP inhibitor UNC0642, UNC0642 inhibitor, G9a inhibitor UNC0642), 10mM (in 1mL DMSO), CAS: 1481677-78-4.
Supplier: Apexbio Technology LLC B77575.1
UNC 0642 (CAS 1481677-78-4) is a selective small-molecule inhibitor targeting lysine methyltransferases G9a and GLP These enzymes catalyze dimethylation of lysine 9 on histone H3 (H3K9) impacting chromatin organization and transcriptional regulation UNC 0642 inhibits G9a enzymatic activity with potent nanomolar affinity (IC50 2 5 nM) in cellular assays It is employed in epigenetic studies investigating G9a/GLP-mediated gene silencing and holds relevance in cancer biology neuroscience and stem cell research
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