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Medchemexpress LLC UNC10217938A | 1347749-97-6 | 99.75% | 456.54 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY13615150MG

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UNC10217938A is a 3-deazapteridine analog with strong oligonucleotide enhancing effects. It enhances oligonucleotides effects by modulating their intracellular trafficking and release from endosomes, and also enhances the effects of antisense and siRNA oligonucleotides.

  • 3-deazapteridine analog with strong oligonucleotide enhancing effects.
  • Enhances oligonucleotide effects by modulating intracellular trafficking and release from endosomes.
  • Enhances the effects of antisense and siRNA oligonucleotides.
  • Strongly enhances luciferase induction in HelaLuc705 cells.
  • Can substantially enhance effects of receptor targeted oligonucleotide conjugates.
  • Can enhance effects of uncharged morpholino oligonucleotides as well as negatively charged oligonucleotides.
  • Causes partial release of oligonucleotide from late endosomes to the cytosol followed by nuclear accumulation.

Catalog No. 50-003-48394


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