Cayman Chemical Uncaa yncopyla sutn 10mg

Supplier:  Cayman Chemical 3640310 MG

An indole with diverse biological activities; selectively inhibits BChE (IC50s = 1.97 and 4.97 µM for the human and horse enzymes, respectively) over AChE, for which it has no activity; an inhibitor of 5-HT3A and 5-HT3AB (IC50s = 65.35 and 28.44 µM, respectively); reduces glutamate-induced increases in cell death in HT22 cells at 50 and 100 µM; induces apoptosis in A549 and H1299 NSCLC cells at 40, 60, and 80 µM; reduces tumor growth and intratumoral levels of phosphorylated GSK3β in an A549 mouse xenograft model at 10 mg/kg; also reduces infarct size and cardiac cell apoptosis and prevents cardiac dysfunction in a rat model of ischemia-reperfusion injury at 20 mg/kg

Catalog No. 50-291-2030