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Vector Laboratories Phaseolus Vulgaris Leucoagglutinin (PHA-L) Unconjugated 5 mg
Supplier: Vector Laboratories L11105
Peanut agglutinin (PNA) binds the T-antigen, a galactosyl (β-1,3) N-acetylgalactosamine structure present in many glycoconjugates, gangliosides, and other soluble and membrane-associated glycoproteins and glycolipids. With exceptions, the glycan that PNA binds PNA is normally sialylated, which prevents binding. PNA can distinguish between normal and tumor tissues and is used to assess malignancy in transitional mucosa. PNA binding is also used to measure cellular maturity in lymphoid tissues, to distinguish a variety of lymphocyte subpopulations in man and experimental animals, and measure the levels of lymphoid cell populations in many diseases. PNA has been used for fractionation of stem cells in mice for use in bone marrow transplantation across histocompatibility barriers. The inhibiting/eluting sugar is 200 mM galactose.
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