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ATCC UPCI:SCC152; Squamous Cell Carcinoma; Human (Homo sapiens)
Supplier: ATCC CRL3240
UPCI:SCC152 is a squamous cell line that was isolated in 1996 from a 47-year-old, white male patient with squamous cell carcinoma, grade 2 from the hypopharynx It was a recurrent tumor. The patient’s original tumor site was the base of the tongue. The UPCI:SCC152 cells are positive for Human Papilloma Virus (HPV). These cells have no TP53 mutations as assayed by sequencing the 5-8 exons of TP53. UPCI:SCC152 showed no amplification of chromosomal band 11q13 using FISH. This cell line was deposited by Susanne M. Gollin, University of Pittsburgh, and can be used for studying the initiation, cancerization, prognosis, intervention and treatment of oral cancers.
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