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Enzo Life Sciences URB-597 (25mg). CAS: 546141-08-6
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Supplier:  Enzo Life Sciences BMLEI3270025

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URB-597 is a potent and selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH), which is involved in the hydrolysis of endogenous cannabinoids such as anandamide. Inhibition of FAAH may serve to enhance the analgesic effects of endogenous cannabinoids. URB-597 has been shown to inhibit FAAH in rat cortical neuron membranes and in intact neurons with IC50 values of 4.6nM and 0.5nM, respectively. The compound has also been shown to have anxiolytic effects in rats (ID50=0.15mg/kg). Because URB-597 acts on FAAH and does not interfere with the binding of anandamide to the CB1 and CB2 receptors, it is a novel tool for drug development. Alternative name: Cyclohexylcarbamic acid 3'-carbamoyl-biphenyl-3-yl ester. Purity: ≥98% (TLC). Solubility: Soluble in 100% ethanol (1mg/ml), dimethyl formamide (10mg/ml) or DMSO (10mg/ml). Long Term Storage: -20°C.

Catalog No. 50-201-0714


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