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Medchemexpress LLC Urea, N-(2-bromophenyl)-N'-[2-[ethyl(3-methylphenyl)amino]ethyl]- | 459429-39-1 | 99.1% | 376.29 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY10845810MG

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SB 452533 is a potent and selective TRPV1 antagonist with a pKb of 7.8. It is intended for research use only.

  • Acts as a potent antagonist at the cloned recombinant rat TRPV1 receptor in HEK293 cells, with a pKb of 7.7 and a pIC50 of 7.0.
  • Reduces the phosphorylation of CAMKK2 and AMPK in skeletal muscle (C2C12) cells.
  • Abolishes Capsaicin's effect of reducing Bleomycin-induced pulmonary fibrosis in BALB/c mice.

Catalog No. 50-003-46913


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