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Medchemexpress LLC Urea, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N' | 1166393-85-6 | 98.6% | 445.52 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY1831250MG

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PF-4618433 is a potent and selective PYK2 inhibitor, with an IC50 of 637 nM. It may be suitable for the research of osteoporosis, craniofacial and appendicular skeletal defects, and for targeted bone regeneration.

  • Potent and selective PYK2 inhibitor with an IC50 of 637 nM.
  • Promotes osteogenesis of hMSC cultures, increasing alkaline phosphatase (ALP) activity and mineralization.
  • Enhances osteoblast proliferation.
  • Enhances calcium deposition.
  • Increases cell proliferation activity in murine bone marrow-derived mesenchymal stem cells (BMSC).

Catalog No. 50-003-87730


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