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Medchemexpress LLC Urea, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N' | 1166393-85-6 | 98.6% | 445.52 | 50 MG

Supplier: Medchemexpress LLC HY1831250MG
PF-4618433 is a potent and selective PYK2 inhibitor, with an IC50 of 637 nM. It may be suitable for the research of osteoporosis, craniofacial and appendicular skeletal defects, and for targeted bone regeneration.
- Potent and selective PYK2 inhibitor with an IC50 of 637 nM.
- Promotes osteogenesis of hMSC cultures, increasing alkaline phosphatase (ALP) activity and mineralization.
- Enhances osteoblast proliferation.
- Enhances calcium deposition.
- Increases cell proliferation activity in murine bone marrow-derived mesenchymal stem cells (BMSC).
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