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Medchemexpress LLC Urea, N-(3,4-difluorophenyl)-N'-(3-methyl-1-phenyl-1H-pyrazol-5-yl)- | 1443246-62-5 | 99.1% | 328.32 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY110192100MG

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ML 297 (VU 0456810) is a potent and selective GIRK1/2 activator with an EC50 of 0.16 μM. It can cross the blood-brain barrier with a brain-to-plasma ratio of 0.2 in a mouse model (i.p.). ML 297 has potential for the treatment of epilepsy.

  • Potent and selective GIRK1/2 activator.
  • Crosses the blood-brain barrier.
  • Potential for the treatment of epilepsy.
  • Prevents convulsions and fatality in a mouse model of epilepsy.

Catalog No. 50-003-43998


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