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Medchemexpress LLC Ureidopropionic acid | 462-88-4 | 98.0% | 132.12 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY11328510MM/1ML

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Ureidopropionic acid is a mitochondrial respiratory chain complex V inhibitor that selectively inhibits the activity of mitochondrial respiratory chain complex V, without affecting complexes I-IV or mitochondrial fatty acid β-oxidation. It promotes neuropathological changes by impairing mitochondrial energy metabolism, oxidative stress, and excitotoxicity pathways.

  • Selectively inhibits mitochondrial respiratory chain complex V.
  • Does not affect complexes I-IV or mitochondrial fatty acid β-oxidation.
  • Induces production of reactive oxygen species.
  • Causes delayed elevation of intracellular calcium concentration.
  • Leads to secondary energy-dependent excitotoxicity and neurodegeneration in neurons.
  • Used in studies related to 3-ureidopropionase deficiency.
  • Used in studies related to severe propionic aciduria.

Catalog No. 50-004-36939


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