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Medchemexpress LLC Uridine 5'-diphosphate (sodium salt) | 21931-53-3 | 98.0% | 10 G
Supplier: Medchemexpress LLC HYW01082010G
Uridine 5'-diphosphate sodium salt is a potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52) and a potent P2Y14 antagonist (pEC50=7.28). It is an endogenous metabolite that catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis.
- Potent, selective P2Y6 receptor native agonist.
- Potent P2Y14 antagonist.
- Endogenous metabolite.
- Catalyzes glucuronidation of various substrates.
- Used in nucleic acid (RNA) biosynthesis.
- Induces microglial CCL2 and CCL3 mRNA expression.
- Induces chemokine expression in microglia and astrocytes through activation of the P2Y6 receptor.
- Induces activation of NFATc1 and NFATc2 in microglia.
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