Medchemexpress LLC Urocortin, rat | 171543-83-2 | 96.6% | 4707.26 | 250 MG

Supplier:  Medchemexpress LLC 250MGHYW011116

Urocortin, rat (Urocortin (Rattus norvegicus)) is a neuropeptide and a potent endogenous CRFR agonist with Kis of 13 nM, 1.5 nM, and 0.97 nM for human CRF1, rat CRF2α and mouse CRF2β, respectively. It is intended for research use only.

• Potent endogenous CRFR agonist.
• Kis of 13 nM, 1.5 nM, and 0.97 nM for human CRF1, rat CRF2α and mouse CRF2β, respectively.
• Induces cyclic AMP (cAMP) generation with EC50 of 0.15 nM, 0.063 nM, and 0.087 nM for human CRF1, rat CRF2α and mouse CRF2β, respectively in stably transfected Chinese hamster ovary cells.
• Decreases food intake in both food-deprived and non-deprived rats (0.01 to 10 μg) and mice (1 μg i.c.v. administration).
• Potential for inducing anxiogenic behavior.

Catalog No. 50-004-51296