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Medchemexpress LLC Uzansertib phosphate | 2088852-47-3 | 99.5% | 611.51 g/mol | C26H29F3N5O7P | 25 MG
Supplier: Medchemexpress LLC HY101870B25MG
Uzansertib phosphate is the phosphate salt of Uzansertib (INCB053914), an orally active, ATP-competitive pan-PIM kinase inhibitor used in preclinical research to probe PIM kinase signaling, inhibit proliferation in hematologic cancer cell lines, and reduce tumor growth in animal models.
- Orally active, ATP-competitive pan-PIM kinase inhibitor.
- Low-nanomolar activity against PIM1, PIM2, and PIM3 (PIM1 0.24 nM; PIM2 30 nM; PIM3 0.12 nM).
- High purity solid, about 99.5% by LCMS.
- Suitable for in vitro and in vivo studies of PIM signaling and downstream phosphorylation (p70S6K/S6, 4E-BP1, BAD).
- White to off-white solid; molecular weight 611.51 g/mol; formula C26H29F3N5O7P.
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