Medchemexpress LLC V-9302 hydrochloride | 2416138-42-4 | 99.1% | 575.14 | 10 MM * 1 ML

Supplier:  Medchemexpress LLC HY112683A10MM/1ML

V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux, selectively targeting the amino acid transporter ASCT2 (SLC1A5) but not ASCT1. It inhibits ASCT2-mediated glutamine uptake with an IC50 of 9.6 μM in HEK-293 cells. This product is for research use only and not intended for patient use. Pharmacological blockade with this compound leads to attenuated cancer cell growth and proliferation, increased cell death, and increased oxidative stress. In vivo, it prevents tumor growth in both HCT-116 and HT29 xenograft models.

• Competitive antagonist of transmembrane glutamine flux
• Selectively targets ASCT2 (SLC1A5)
• Inhibits ASCT2-mediated glutamine uptake with an IC50 of 9.6 μM
• Attenuates cancer cell growth and proliferation
• Increases cell death and oxidative stress
• Prevents tumor growth in xenograft models

Catalog No. 50-004-37885