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Medchemexpress LLC V-9302 hydrochloride | 2416138-42-4 | 99.10% | 575.14 | 100 MG
Supplier: Medchemexpress LLC HY112683A100MG
V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. It selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) but not ASCT1. It inhibits ASCT2-mediated glutamine uptake (IC50=9.6 μM) in HEK-293 cells.
- Competitive antagonist of transmembrane glutamine flux.
- Selectively targets amino acid transporter ASCT2 (SLC1A5).
- Potently inhibits ASCT2-mediated glutamine uptake.
- Attenuates cancer cell growth and proliferation.
- Increases cell death and oxidative stress.
- Prevents tumor growth in xenograft models.
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