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Medchemexpress LLC Vabicaserin hydrochloride | 887258-94-8 | 99.5% | 264.79 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY111200100MG

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Vabicaserin hydrochloride is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM.

  • Displaces 125I-(2,5-dimethoxy)phenylisopropylamine binding from human 5-HT2C receptor sites.
  • Ki value of 3 nM and >50-fold selective over serotonergic, noradrenergic, and dopaminergic receptors.
  • Potent and full agonist in stimulating 5-HT2C receptor-coupled calcium mobilization.
  • Exhibits 5-HT2A receptor antagonism.
  • Exhibits 5-HT2B antagonist or partial agonist activity in transfected cells.

Catalog No. 50-003-43835


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