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Medchemexpress LLC Vacuolin-1 | 351986-85-1 | MFCD00321410 | 98.5% | 577.42 | C26H24IN7O | 5 MG
Supplier: Medchemexpress LLC HY1186305MG
Vacuolin-1 (CAS 351986-85-1) is a cell-permeable small molecule that inhibits PIKfyve and blocks Ca2+-dependent lysosomal exocytosis. It impairs lysosomal maturation, inhibits late-stage autophagy, and induces vacuole formation, making it useful for studying endosomal/lysosomal trafficking and membrane dynamics in cell biology research.
- Potent, cell-permeable PIKfyve inhibitor.
- Blocks Ca2+-dependent lysosomal exocytosis in cells.
- Impairs lysosomal maturation and inhibits late-stage autophagy.
- Induces vacuole formation and alters endosomal/lysosomal trafficking.
- Provided at high purity for research applications.
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