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Medchemexpress LLC Val-cit-pab-mmae | 644981-35-1 | 1123.43 | C58H94N10O12 | 5 MG
SDP

Catalog No. 5000213303
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Val-Cit-PAB-MMAE is a drug-linker conjugate intended for antibody-drug conjugate (ADC) research. It links a protease-cleavable Val-Cit-PAB peptide to the cytotoxic payload monomethyl auristatin E (MMAE), enabling intracellular release of the payload upon proteolytic cleavage. The compound is provided as a solid and requires cold storage; solutions are unstable and should be prepared fresh.

  • Protease-cleavable Val-Cit-PAB linker for controlled intracellular release.
  • Contains potent tubulin inhibitor MMAE as the cytotoxic payload.
  • High solubility in DMSO; multiple in vivo formulation options documented.
  • Supplied as a solid; store at 4°C under nitrogen.
  • Suitable for ADC synthesis and conjugation optimization studies.

Catalog No. 50-002-13303 Supplier Medchemexpress LLC Supplier No. HY1003745MG
May include imposed supplier surcharges.
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Val-Cit-PAB-MMAE is a drug-linker conjugate intended for antibody-drug conjugate (ADC) research. It links a protease-cleavable Val-Cit-PAB peptide to the cytotoxic payload monomethyl auristatin E (MMAE), enabling intracellular release of the payload upon proteolytic cleavage. The compound is provided as a solid and requires cold storage; solutions are unstable and should be prepared fresh.

  • Protease-cleavable Val-Cit-PAB linker for controlled intracellular release.
  • Contains potent tubulin inhibitor MMAE as the cytotoxic payload.
  • High solubility in DMSO; multiple in vivo formulation options documented.
  • Supplied as a solid; store at 4°C under nitrogen.
  • Suitable for ADC synthesis and conjugation optimization studies.

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