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Medchemexpress LLC Valacyclovir hydrochloride | 124832-27-5 | 99.9% | 360.80 | 100 MG
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Supplier:  Medchemexpress LLC HY17425A100MG

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Valacyclovir hydrochloride is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. It inhibits HSV-1 W (50=2.9 μg/ml) and is a proagent of Aciclovir.

  • IC50 and target: HSV-1, 2.9 μg/mL (IC50).
  • In vitro: Uptake is concentration dependent and saturable, with hPEPT1 dominating intestinal transport.
  • In vivo: Effective for treating genital herpes (1 g twice daily) and recurrences. A 1 g daily dose is as effective as 2 g daily and can be administered once a day. Studies in immunosuppressed mice showed reduced erythema, eliminated ear paralysis, ear lesions, and death.

Catalog No. 50-003-86102


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