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Medchemexpress LLC Valategrast (R-411 free base) | 220847-86-9 | 97.1% | C30H32Cl3N3O4 | 100 MG
Supplier: Medchemexpress LLC HY14190100MG
Valategrast (R-411 free base) is a potent and orally active dual antagonist of integrin α4β1 (VLA-4) and α4β7, showing potential for treating Chronic Obstructive Pulmonary Disease (COPD) and asthma. It features a l-phenylalanine-N-aroyl motif, with its carboxylic acid binding to the metal ion in the metal-ion-dependent adhesion site (MIDAS).
- CAS no.: 220847-86-9
- Molecular weight: 604.95
- Formula: C30H32Cl3N3O4
- Appearance: Off-white to light yellow solid
- Solubility: ≥ 4.25 mg/mL (7.03 mM) in various in vivo dissolution methods
- Storage: -80°C, stored under nitrogen
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