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Medchemexpress LLC Valategrast (R-411 free base) | 220847-86-9 | 97.1% | C30H32Cl3N3O4 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY1419050MG

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Valategrast (R-411 free base) is a potent and orally active integrin α4β1 (VLA-4) and α4β7 dual antagonist. It is being investigated for its potential in treating Chronic Obstructive Pulmonary Disease (COPD) and asthma. It contains a common l-phenylalanine-N-aroyl motif where the carboxylic acid binds to the metal ion in the metal-ion-dependent adhesion site (MIDAS).

  • Potent and orally active integrin α4β1 (VLA-4) and α4β7 dual antagonist.
  • Potential for treating Chronic Obstructive Pulmonary Disease (COPD).
  • Potential for treating asthma.
  • Contains an l-phenylalanine-N-aroyl motif for binding to the metal ion in the MIDAS site.

Catalog No. 50-003-55068


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