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Cayman Chemical ValerenIc AcId 1mg
SDP

Catalog No. 502944484
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A sesquiterpenoid with diverse biological activities; selectively RXRβ over RXRα and RXRγ in reporter assays using HEK293T cells (EC50s = 5.2, 27, and 43 µM, respectively), as well as RARs, PPARs, LXRs, FXR, CAR, VDR, and PXR at 30 µM; enhances GABA-induced activation of α1β2γ2-subunit containing GABA receptors in CHO cells (EC50 = 12.6 µM); cytotoxic to GLC-4 and COLO 320 cells (IC50s = 127 and 124 µM, respectively); decreases motor performance in the rotarod test and increases pentobarbital-induced sleeping time in mice at 100 mg/kg, i.p.; increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity, at 12 mg/kg

Catalog No. 50-294-4484 Supplier Cayman Chemical Supplier No. 401131 MG
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A sesquiterpenoid with diverse biological activities; selectively RXRβ over RXRα and RXRγ in reporter assays using HEK293T cells (EC50s = 5.2, 27, and 43 µM, respectively), as well as RARs, PPARs, LXRs, FXR, CAR, VDR, and PXR at 30 µM; enhances GABA-induced activation of α1β2γ2-subunit containing GABA receptors in CHO cells (EC50 = 12.6 µM); cytotoxic to GLC-4 and COLO 320 cells (IC50s = 127 and 124 µM, respectively); decreases motor performance in the rotarod test and increases pentobarbital-induced sleeping time in mice at 100 mg/kg, i.p.; increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity, at 12 mg/kg

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