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Cayman Chemical ValproIc AcId 100g
Supplier: Cayman Chemical 35739100 G
An analog of valeric acid; inhibits class I HDACs (IC50s = ~2 mM); decreases the number of axon branches in sensory neurons isolated from newborn rat dorsal root ganglia; inhibits amyloid-β deposition and neuritic plaque formation and decreases escape latency in the Morris water maze test in the APP23 transgenic mouse model of Alzheimer's disease; has anticonvulsant activity in the pentylenetetrazole seizure threshold test in mice (ED50 = 0.71 mmol/kg); induces neurotoxicity at ≥1.2 mmol/kg
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