Thermo Scientific Chemicals Vancomycin hydrochloride, Molecular Biology Grade

Description

Vancomycin hydrochloride (vancomycin HCl, CAS # 1404-93-9) is the hydrochloride salt of the bactericidal agent, vancomycin. | CAS: 1404-93-9 | C66H76Cl3N9O24 | 1485.72 g/mol

Inhibits bacterial mucopeptide synthesis.Vancomycin hydrochloride is used as an antiviral and anti bacterial. binds to bacterial cell wall. It exhibits potent activity against Gram positive bacteria and is highly effective against MRSA.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Vancomycin hydrochloride is a glycopeptide antibiotic that prevents cell wall synthesis
• Originally obtained from the bacterial strain Streptomyces Orientalis
• Vancomycin binds to D-alanyl-D-alanine motifs in cell wall precursors and leads to cell death
• It is active against some penicillin-resistant bacteria

Application

• Vancomycin hydrochloride is intended for use in the research of infections and for antibiotic resistance testing

Specifications

Chemical Identifiers

• CAS: 1404-93-9
• Molecular Formula: C66H76Cl3N9O24
• Molecular Weight (g/mol): 1485.72
• MDL Number: MFCD03613611,MFCD03613611
• InChI Key: LCTORFDMHNKUSG-UHFFFAOYNA-N
• PubChem CID: 124080918
• IUPAC Name: 48-({3-[(4-amino-5-hydroxy-4,6-dimethyloxan-2-yl)oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl}oxy)-22-(carbamoylmethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2³,⁶.2¹⁴,¹⁷.1⁸,¹².1²⁹,³³.0¹⁰,²⁵.0³⁴,³⁹]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride
• SMILES: Cl.CNC(CC(C)C)C(=O)NC1C(O)C2=CC(Cl)=C(OC3=CC4=CC(OC5=C(Cl)C=C(C=C5)C(O)C5NC(=O)C(NC(=O)C4NC(=O)C(CC(N)=O)NC1=O)C1=CC(=C(O)C=C1)C1=C(O)C=C(O)C=C1C(NC5=O)C(O)=O)=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1)C=C2

• Type: Vancomycin Hydrochloride
• Physical Form: Powder
• Color: White
• Quantity: 1 g
• Sensitivity: Hygroscopic
• Beilstein: 3704657
• Merck Index: 149929
• Solubility Information: Soluble in water; Slightly soluble in methanol,ethanol and dimethylsulfoxide.
• Formula Weight: 1485.73
• Grade: Molecular Biology
• Chemical Name or Material: Vancomycin hydrochloride

Safety and Handling

Hazard Category	Serious eye damage/eye irritation (category 2), Specific target organ toxicity after single exposure (category 3), Skin sensitisation (category 1), Skin corrosion/irritation (category 2)
Hazard Statement	Causes serious eye irritation, May cause respiratory irritation, May cause an allergic skin reaction, Causes skin irritation
RTECSNumber	YW4380000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only