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Medchemexpress LLC Vardenafil hydrochloride trihydrate | 330808-88-3 | 99.7% | 1 ML
Supplier: Medchemexpress LLC HYB0442B10MM/1ML
Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. It shows inhibitory effects towards PDE1 and PDE6 with IC50s of 180 nM and 11 nM, respectively, while its IC50s are >1000 nM for PDE3 and PDE4. This compound competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis, thereby increasing cGMP levels.
- Selective and orally active inhibitor of phosphodiesterase-5 (PDE5).
- Competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis.
- Increases cGMP levels.
- Can be used for research related to erectile dysfunction, hepatitis, and diabetes.
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