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Medchemexpress LLC VAS 3947 | 869853-70-3 | 99.59% | 310.33 | 1 G
Supplier: Medchemexpress LLC HY111447100MG
VAS 3947 is a specific NADPH oxidase (NOX) inhibitor that has a potent antiplatelet effect. It induces apoptosis independently of anti-NOX activity through UPR activation, primarily due to protein aggregation and misfolding.
- Specific NADPH oxidase (NOX) inhibitor.
- Exerts a potent antiplatelet effect.
- Induces apoptosis independently of anti-NOX activity via UPR activation.
- Inhibits NADPH oxidase activity in low micromolar concentrations.
- Does not interfere with ROS detection, XOD, or eNOS activities.
- Triggers cell proliferation arrest and death.
- Attenuates platelet activation and thrombus formation via a NOX-independent pathway downstream of PKC.
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