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Medchemexpress LLC Vasculotide TFA | 99.66% | 14000 (average) | 1 MG

Supplier: Medchemexpress LLC HYP10580A1MG
Vasculotide TFA is an angiopoietin-1 mimetic that activates Tie-2, inducing its phosphorylation. It exhibits anti-inflammatory and anti-permeability effects, ameliorating endotoxin-induced endothelial barrier dysfunction and promoting angiogenesis in a mouse model of diabetic ulcer. It also protects mice from vascular leakage, reduces mortality in murine abdominal sepsis, and decreases microvascular leakage while improving microcirculatory perfusion in a rat model of hemorrhagic shock.
- Activates Tie-2 and induces its phosphorylation
- Exhibits anti-inflammatory and anti-permeability effects
- Promotes angiogenesis
- Protects against vascular leakage and reduces mortality in sepsis models
- Improves microcirculatory perfusion
- For research use only
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